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doi: 10.2337/db13-0604 30 Lam-ChungCE

The SURMOUNT-5 trial, published in The New England Journal of Medicine in May 2025, is the first large randomized study to compare tirzepatide and semaglutide directly in adults with obesity

E., & James, S

Molecular Cell

Previous studies have demonstrated that HSPs and their co-chaperones are involved in modulating the interaction between estrogen receptors and estradiol, as well as in regulating estrogen receptormediated cell proliferation [74, 75]